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Article

The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models?

Journal of muscle research and cell motility - 1 Feb 2015

Canato Marta, Capitanio Paola, Reggiani Carlo, Cancellara Lina

Abstract excerpt

Calcium storage, release, and reuptake are essential for normal physiological function of muscle. Several human skeletal muscle disorders can arise from dysfunction in the control and coordination of these three critical processes. The release from the Sarcoplasmic Reticulum stores (SR) is handled by a multiprotein complex called Calcium Release Unit and composed of DiHydroPyridine Receptor or DHPR, Ryanodine...

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Identifiers

PMID: 25424378
DOI: 10.1007/s10974-014-9396-7

Genes

RYR1
CASQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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