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Article

Functional expression of transgenic 1sDHPR channels in adult mammalian skeletal muscle fibres.

The Journal of physiology - 15 Mar 2011

DiFranco Marino, Tran Philip, Quiñonez Marbella, Vergara Julio L

Abstract excerpt

We investigated the effects of the overexpression of two enhanced green fluorescent protein (EGFP)-tagged α1sDHPR variants on Ca2+ currents (ICa), charge movements (Q) and SR Ca2+ release of muscle fibres isolated from adult mice. Flexor digitorum brevis (FDB)muscles were transfected by in vivo electroporation with plasmids encoding for EGFP-α1sDHPR-wt and EGFP-α1sDHPR-T935Y (an isradipine-insensitive mutant)....

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Identifiers

PMID: 21262876
DOI: 10.1113/jphysiol.2010.202804
PMCID: PMC3082101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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