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Roles of plant retinoblastoma protein: cell cycle and beyond

31 Aug 2020

Abstract excerpt

The human retinoblastoma (RB1) protein is a tumor suppressor that negatively regulates cell cycle progression through its interaction with members of the E2F/DP family of transcription factors. However, RB-related (RBR) proteins are an early acquisition during eukaryote evolution present in plant lineages, including unicellular algae, ancient plants (ferns, lycophytes, liverworts, mosses), gymnosperms, and...

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Cancer-related Molecular Pathways
Plant Molecular Biology Research
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32865261
DOI: 10.15252/embj.2020105802

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