Article
Recurrent BRCA1 Mutation, but no BRCA2 Mutation, in Vietnamese Patients with Ovarian Carcinoma Detected with Next Generation Sequencing.
Asian Pacific journal of cancer prevention : APJCP - 1 Aug 2020
Vu Hoang Anh, Phu Ngo Dai, Khuong Le Thai, Hoa Pham Huy, Nhu Bui Thi Hong, Nhan Vo Thanh, Thanh Le Quang, Sinh Nguyen Duy, Chi Hoang Thanh, Quan Nguyen Dang, Binh Nguyen Trong
Abstract excerpt
BACKGROUND: Identification of germline and somatic BRCA1/2 mutations in ovarian cancer is important for genetic counseling and treatment decision making with poly ADP ribose polymerase inhibitors. Unfortunately, data on the frequency of BRCA1/2 mutations in Vietnamese patients are scare. METHODS: We aim to explore the occurrence of BRCA1/2 mutations in 101 Vietnamese patients with ovarian cancer including serous...
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