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Article

Prevalence of BRCA1 and BRCA2 pathogenic sequence variants in ovarian cancer patients in the Gulf region: the PREDICT study.

BMC cancer - 20 Dec 2021

Azribi Fathi, Abdou Ehab, Dawoud Emad, Ashour Mohamed, Kamal Amgad, Al Sayed Mohamed, Burney Ikram

Abstract excerpt

BACKGROUND: Patients with pathogenic sequence variants (PSVs) in BRCA1/BRCA2 are at high risk of developing ovarian cancer (OC). However, genetic testing for BRCA1/BRCA2 PSVs is still not a routine practice in the Middle East. With the lack of epidemiological studies in the region, we aim to describe the prevalence of BRCA1/BRCA2 PSVs in patients with OC across different countries in the Gulf region. METHODS: The...

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PMID: 34930165
DOI: 10.1186/s12885-021-09094-8
PMCID: PMC8690897

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