Article
Construction of IMMS Containing Multi-site Liposomes for Dynamic Monitoring of Blood CTC in Patients with Osimertinib-resistant Non-small-cell Lung Cancer and its Mechanism.
Anti-cancer agents in medicinal chemistry - 1 Jan 2023
Chen Xiaoju, Luo Ling, Lu Yanyan, Qiu Ye, Liang Jie, Chen Yulin, Ning Yufang, Li Bixun
Abstract excerpt
OBJECTIVE: This article aims to establish a liquid biopsy system for gene detection of circulating tumor cells (CTC) in lung cancer, systematically analyze the significance of osimertinib resistance, and formulate an individualized diagnosis and treatment plan. METHODS: Liposome-contained magnetic microspheres coated with Fe3O4 nanoparticles were synthesized by microemulsion, and the surface was modified with...
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