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Puerarin alleviates cisplatin‑induced acute renal damage and upregulates microRNA‑31‑related signaling

29 Jul 2020

Abstract excerpt

Cisplatin (DDP) is a commonly used chemotherapy drug; however, the side effects associated with its use, particularly acute kidney injury (AKI), limit its clinical application. Puerarin is a natural flavonoid extracted from the Chinese medical herb Radix puerariae, which has been reported to alleviate DDP‑induced nephrotoxicity. However, the mechanisms underlying puerarin regulation on microRNA (miR)‑31‑mediated...

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PMID: 32855680
DOI: 10.3892/etm.2020.9081

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