Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Statins: Epidrugs with effects on endothelial health?

28 Aug 2020

Abstract excerpt

BACKGROUND: Epigenetic events involving the methylation of CpG cites in DNA, histone modifications and noncoding RNAs correlated with many essential processes in human cells and diseases, such as cancer and cardiovascular diseases. HMG-CoA reductase inhibitors (statins)-the LDL cholesterol-lowering drugs-are broadly used in cardio- and cerebro-vascular diseases. It is well established that statins exert...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Kruppel-like factors research
Share to Lipoproteins and Cardiovascular Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32854143
DOI: 10.1111/eci.13388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Statins: Epidrugs with effects on endothelial health?PMID 32854143Read ↗

Epigenetics is involved in the pleiotropic effects of statinsSemantic proximity Read ↗

Simvastatin rescues vascular health by targeting epigenetic-regulated endothelial-to-mesenchymal transition: a revival of pleiotropic effects?Semantic proximity Read ↗

Epidrugs in the clinical management of atherosclerosis: Mechanisms, challenges and promisesSemantic proximity Read ↗

Epigenetic Biomarkers in Cardiovascular DiseasesSemantic proximity Read ↗

Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular diseaseSemantic proximity Read ↗

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1Semantic proximity Read ↗

The pharmaco-epigenetics of hypertension: a focus on microRNASemantic proximity Read ↗

Natural Bioproducts with Epigenetic Properties for Treating Cardiovascular DisordersSemantic proximity Read ↗

Histone modification of endothelial-mesenchymal transition in cardiovascular diseasesSemantic proximity Read ↗

Statins are potential anticancerous agents (Review)Semantic proximity Read ↗

Statins personalized.Semantic proximity Read ↗

Treatment of cardiovascular pathology with epigenetically active agents: Focus on natural and synthetic inhibitors of DNA methylation and histone deacetylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.