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Epidrugs in the clinical management of atherosclerosis: Mechanisms, challenges and promises

20 Jul 2024

Abstract excerpt

Atherosclerosis is a complex and multigenic pathology associated with significant epigenetic reprogramming. Traditional factors (age, sex, obesity, hyperglycaemia, dyslipidaemia, hypertension) and non-traditional factors (foetal indices, microbiome alteration, clonal hematopoiesis, air pollution, sleep disorders) induce endothelial dysfunction, resulting in reduced vascular tone and increased vascular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39038635
DOI: 10.1016/j.ejphar.2024.176827

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