Article
PopHumanVar: an interactive application for the functional characterization and prioritization of adaptive genomic variants in humans.
Nucleic acids research - 7 Jan 2022
Colomer-Vilaplana Aina, Murga-Moreno Jesús, Canalda-Baltrons Aleix, Inserte Clara, Soto Daniel, Coronado-Zamora Marta, Barbadilla Antonio, Casillas Sònia
Abstract excerpt
Adaptive challenges that humans faced as they expanded across the globe left specific molecular footprints that can be decoded in our today's genomes. Different sets of metrics are used to identify genomic regions that have undergone selection. However, there are fewer methods capable of pinpointing the allele ultimately responsible for this selection. Here, we present PopHumanVar, an interactive online...
Topics
- Adaptation, Physiological
- Computational Biology
- Databases, Genetic
- Genome, Human
- Genomics
- Humans
- Polymorphism, Single Nucleotide
- Selection, Genetic
- Software