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Article

Localization of adaptive variants in human genomes using averaged one-dependence estimation.

Nature communications - 19 Feb 2018

Sugden Lauren Alpert, Atkinson Elizabeth G, Fischer Annie P, Rong Stephen, Henn Brenna M, Ramachandran Sohini

Abstract excerpt

Statistical methods for identifying adaptive mutations from population genetic data face several obstacles: assessing the significance of genomic outliers, integrating correlated measures of selection into one analytic framework, and distinguishing adaptive variants from hitchhiking neutral variants. Here, we introduce SWIF(r), a probabilistic method that detects selective sweeps by learning the distributions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29459739
DOI: 10.1038/s41467-018-03100-7
PMCID: PMC5818606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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