Article

The enteric pathogen <i>Cryptosporidium parvum</i> exports proteins into the cytoplasm of the infected host cell

2021-06-04

Abstract excerpt

<h4>ABSTRACT</h4> The parasite Cryptosporidium is responsible for diarrheal disease in young children causing death, malnutrition, and growth delay. Cryptosporidium invades enterocytes where it develops in a unique intracellular niche. Infected cells exhibit profound changes in morphology, physiology and transcriptional activity. How the parasite effects these changes is poorly understood. We explored the local...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 703ea189-96b6-5a1f-8fc1-1fe3e55f5858
DOI: 10.1101/2021.06.04.447155

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The enteric pathogen <i>Cryptosporidium parvum</i> exports proteins into the cytoplasm of the infected host cellDOI 10.1101/2021.06.04.447155Read

Cryptosporidium modifies intestinal microvilli through an exported virulence factorSemantic proximity Read

Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of <i>Cryptosporidium parvum</i> using the dynamic TIM-1 gastrointestinal modelSemantic proximity Read

Investigating <em>Cryptosporidium</em> spp. Using Genomic and Proteomic Techniques: Current Progress and Future DirectionsSemantic proximity Read

Determining the protein repertoire of <b><i>Cryptosporidium parvum</i></b> sporozoitesSemantic proximity Read

Non-coding RNAs in epithelial immunity to<i>Cryptosporidium</i>infectionSemantic proximity Read

Unveiling <i>Cryptosporidium parvum</i> Sporozoite-Derived Extracellular Vesicles: Profiling, Origin, and Protein CompositionSemantic proximity Read

Exploring the Repertoire of Rhomboid Proteases in <i>Cryptosporidium parvum</i> Parasite: Phylogenesis, Structural motifs and Cellular Localization in Sporozoite CellsSemantic proximity Read

Dendritic cell-mediated responses to secreted <i>Cryptosporidium</i> effectors are required for parasite-specific CD8 <sup>+</sup> T cell responsesSemantic proximity Read

Investigating Cryptosporidium spp. Using Genomic, Proteomic and Transcriptomic Techniques: Current Progress and Future DirectionsSemantic proximity Read

Insulinase like protease 1 contributes to macrogamont formation in <i>Cryptosporidium parvum</i>Semantic proximity Read

A genetic screen identifies a protective type III interferon response to <i>Cryptosporidium</i> that requires TLR3 dependent recognitionSemantic proximity Read

Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cellSemantic proximity Read