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Senolytic CAR T Cells in Solid Tumors and Age-Related Pathologies

25 Aug 2020

Abstract excerpt

Cellular senescence is implicated as a contributing factor in the pathology of several age-related disorders and cancer development. Therefore, targeted removal of senescent cells has emerged as a promising treatment strategy for these conditions. However, current senolytic strategies that selectively eliminate senescent cells are limited by their toxicity and lack of potency. A recent study reported on the use...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32841587
DOI: 10.1016/j.ymthe.2020.08.011

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