Article
Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies Suggestive Loci for Sodium Intake, Potassium Intake, and Their Ratio Measured from 24-Hour or Half-Day Urine Samples.
The Journal of nutrition - 12 Oct 2020
Kho Minjung, Smith Jennifer A, Verweij Niek, Shang Lulu, Ryan Kathleen A, Zhao Wei, Ware Erin B, Gansevoort Ron T, Irvin Marguerite R, Lee Jung Eun, Turner Stephen T, Sung Joohon, van der Harst Pim, Arnett Donna K, Baylin Ana, Park Sung Kyun, Seo Young Ah, Kelly Kristen M, Chang Yen Pei C, Zhou Xiang, Lieske John C, Kardia Sharon L R
Abstract excerpt
BACKGROUND: Excess sodium intake and insufficient potassium intake are risk factors for hypertension, but there is limited knowledge regarding genetic factors that influence intake. Twenty-hour or half-day urine samples provide robust estimates of sodium and potassium intake, outperforming other measures such as spot urine samples and dietary self-reporting. OBJECTIVE: The aim of this study was to investigate...
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