Article
Novel mutations in the PLCZ1 gene associated with human low or failed fertilization
24 Aug 2020
Abstract excerpt
BACKGROUND: Fertilization failure (FF) is a complex reproductive disorder characterized by the failure of pronuclei formation during fertilization. In addition to some cases caused by iatrogenic problems and known genetic factors, there are still many unexplained aspects of FF. Here, we aimed to assess the clinical and genetic characteristics of two families experiencing primary infertility with FF. METHODS: We...
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