Article
A population-based phenome-wide association study of cardiac and aortic structure and function.
Nature medicine - 1 Oct 2020
Bai Wenjia, Suzuki Hideaki, Huang Jian, Francis Catherine, Wang Shuo, Tarroni Giacomo, Guitton Florian, Aung Nay, Fung Kenneth, Petersen Steffen E, Piechnik Stefan K, Neubauer Stefan, Evangelou Evangelos, Dehghan Abbas, O'Regan Declan P, Wilkins Martin R, Guo Yike, Matthews Paul M, Rueckert Daniel
Abstract excerpt
Differences in cardiac and aortic structure and function are associated with cardiovascular diseases and a wide range of other types of disease. Here we analyzed cardiovascular magnetic resonance images from a population-based study, the UK Biobank, using an automated machine-learning-based analysis pipeline. We report a comprehensive range of structural and functional phenotypes for the heart and aorta across...
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