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Article

GBAT: a gene-based association test for robust detection of trans-gene regulation.

Genome biology - 24 Aug 2020

Liu Xuanyao, Mefford Joel A, Dahl Andrew, He Yuan, Subramaniam Meena, Battle Alexis, Price Alkes L, Zaitlen Noah

Abstract excerpt

The observation that disease-associated genetic variants typically reside outside of exons has inspired widespread investigation into the genetic basis of transcriptional regulation. While associations between the mRNA abundance of a gene and its proximal SNPs (cis-eQTLs) are now readily identified, identification of high-quality distal associations (trans-eQTLs) has been limited by a heavy multiple testing...

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Identifiers

PMID: 32831138
DOI: 10.1186/s13059-020-02120-1
PMCID: PMC7444084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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