Article
Common mechanisms for type 2 diabetes and psychosis: Findings from a prospective birth cohort.
Schizophrenia research - 1 Sept 2020
Perry Benjamin I, Jones Hannah J, Richardson Tom G, Zammit Stan, Wareham Nicholas J, Lewis Glyn, Jones Peter B, Khandaker Golam M
Abstract excerpt
BACKGROUND: Psychosis and type 2 diabetes mellitus (T2DM) are commonly comorbid and may share pathophysiologic mechanisms. To investigate shared genetic variation and inflammation as potential common mechanisms, we tested: (i) associations between genetic predisposition for T2DM and psychotic experiences and psychotic disorder in young adults; (ii) the association between genetic predisposition for schizophrenia...
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