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Article

Mechanisms Underlying the Comorbidity of Schizophrenia and Type 2 Diabetes Mellitus.

The international journal of neuropsychopharmacology - 18 May 2021

Mizuki Yutaka, Sakamoto Shinji, Okahisa Yuko, Yada Yuji, Hashimoto Nozomu, Takaki Manabu, Yamada Norihito

Abstract excerpt

The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10 to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among the main reasons. The prevalence of T2DM in patients with schizophrenia may be epidemiologically frequent because antipsychotics induce weight gain as a side effect and the cognitive dysfunction of patients with schizophrenia...

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PMID: 33315097
DOI: 10.1093/ijnp/pyaa097
PMCID: PMC8130204

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