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Article

Inherited risk factors for thrombotic diseases in children: the genome-wide perspective.

Seminars in thrombosis and hemostasis - 1 Oct 2011

Preuss Christoph, Stoll Monika

Abstract excerpt

As a result of technological advances in the field of high-throughput genomics, there has been a remarkable transition in studying the nature of complex genetic disorders. The genetic analysis of prothrombotic risk factors has shifted from candidate gene to genome-wide association studies (GWAS) in adults. GWAS established a framework in which up to 90% of common genetic variation can be analyzed in a single...

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PMID: 22187409
DOI: 10.1055/s-0031-1297177

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