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Article

ADAMTS proteins in human disorders.

Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2018

Mead Timothy J, Apte Suneel S

Abstract excerpt

ADAMTS proteins are a superfamily of 26 secreted molecules comprising two related, but distinct families. ADAMTS proteases are zinc metalloendopeptidases, most of whose substrates are extracellular matrix (ECM) components, whereas ADAMTS-like proteins lack a metalloprotease domain, reside in the ECM and have regulatory roles vis-à-vis ECM assembly and/or ADAMTS activity. Evolutionary conservation and expansion of...

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Source

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Identifiers

PMID: 29885460
DOI: 10.1016/j.matbio.2018.06.002
PMCID: PMC6146047

Genes

ADAMTS13
ADAMTS10
ADAMTS17
ADAMTS2
ADAMTS20
ADAMTS3
ADAMTS5
ADAMTS7
ADAMTSL2
ADAMTSL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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