Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells

19 Aug 2020

Abstract excerpt

Comparison of 10 co-receptor variant CARs revealed a requirement for CD28wt for optimal suppression by human regulatory T cells.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32817364
DOI: 10.1126/scitranslmed.aaz3866

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cellsPMID 32817364Read ↗

Functional effects of chimeric antigen receptor co-receptor signaling domains in human TregsSemantic proximity Read ↗

High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cellsSemantic proximity Read ↗

Chimeric antigen receptor signaling: Functional consequences and design implicationsSemantic proximity Read ↗

Antigen‐specific targeting of CD28‐mediated T cell co‐stimulation using chimeric single‐chain antibody variable fragment‐CD28 receptorsSemantic proximity Read ↗

Integration of exogenous and endogenous co-stimulatory signals by CAR-TregsSemantic proximity Read ↗

Fully human CD19-specific chimeric antigen receptors for T-cell therapySemantic proximity Read ↗

B7-H5 costimulates human T cells via CD28HSemantic proximity Read ↗

Selecting costimulatory domains for chimeric antigen receptors: functional and clinical considerationsSemantic proximity Read ↗

Molecular and genetic insights into T-cell antigen receptor signaling.Semantic proximity Read ↗

Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densitiesSemantic proximity Read ↗

Considering B7-CD28 as a family through sequence and structureSemantic proximity Read ↗

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.