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Article

Genetic associations of myopia severities and endophenotypes in children.

The British journal of ophthalmology - 1 Aug 2021

Li Fen Fen, Lu Shi Yao, Tang Shu Min, Kam Ka Wai, Pancy O S Tam, Yip Wilson W K, Young Alvin L, Tham Clement C, Pang Chi Pui, Yam Jason C, Chen Li Jia

Abstract excerpt

OBJECTIVE: To investigate the associations of multiple single-nucleotide polymorphisms (SNPs) with the severities and endophenotypes of myopia in children. METHODS: A total of 3300 children aged 5-10 years were recruited: 137 moderate and high myopia (SE≤-3.0D), 670 mild myopia (-3.0D<SE≤-0.5D) and 2493 controls (SE>-0.5D). 13 SNPs in 13 genes/loci were selected for genotyping in all subjects using TaqMan assays....

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Identifiers

PMID: 32816751
DOI: 10.1136/bjophthalmol-2020-316728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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