Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endophenotyping reveals differential phenotype-genotype correlations between myopia-associated polymorphisms and eye biometric parameters.

Molecular vision - 1 Jan 2012

Chen Jian Huan, Chen Haoyu, Huang Shulan, Lin Jianwei, Zheng Yuqian, Xie Mingliang, Lin Wenjie, Pang Chi Pui, Zhang Mingzhi

Abstract excerpt

PURPOSE: To investigate the association with ocular biometric parameters in myopia-associated single nucleotide polymorphisms (SNPs) of the gap junction protein delta 2 (GJD2), insulin-like growth factor-1 (IGF1) and hepatocyte growth factor (HGF) genes in two geographically different Chinese cohorts. METHODS: In 814 unrelated Han Chinese individuals aged above 50 years including 362 inland residents and 432...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biometry
Share to Connexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Geography

Share to Hepatocyte Growth Factor

Share to Insulin-Like Growth Factor I

Share to Linkage Disequilibrium

Share to Myopia

Source

Open in PubMed Open full text

Identifiers

PMID: 22509107
PMCID: PMC3324351

Genes

GJD2
HGF
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endophenotyping reveals differential phenotype-genotype correlations between myopia-associated polymorphisms and eye biometric parameters.PMID 22509107Read ↗

Genetic associations of myopia severities and endophenotypes in children.Semantic proximity Read ↗

Phenotypic Consequences of the GJD2 Risk Genotype in Myopia Development.Semantic proximity Read ↗

IMI – Myopia Genetics ReportSemantic proximity Read ↗

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.Semantic proximity Read ↗

Identification of novel loci influencing refractive error in East Asian populations using an extreme phenotype design.Semantic proximity Read ↗

IMI-Myopia Genetics Report.Semantic proximity Read ↗

Comprehensive replication of the relationship between myopia-related genes and refractive errors in a large Japanese cohort.Semantic proximity Read ↗

Update on the epidemiology and genetics of myopic refractive errorSemantic proximity Read ↗

Novel loci for ocular axial length identified through extreme-phenotype genome-wide association study in Chinese populations.Semantic proximity Read ↗

Genome-wide association studies of refractive error and myopia, lessons learned, and implications for the future.Semantic proximity Read ↗

Nature and nurture: the complex genetics of myopia and refractive error.Semantic proximity Read ↗

ExGRS: exome-wide genetic risk score to predict high myopia across multi-ancestry populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.