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Article

Allelic Distribution of Genes for Apolipoprotein E and MTHFR in Patients with Alzheimer's Disease and Their Epistatic Interaction.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Sutovsky Stanislav, Petrovic Robert, Fischerova Maria, Haverlikova Viera, Ukropcova Barbara, Ukropec Jozef, Turcani Peter

Abstract excerpt

BACKGROUND: Genetic risk factors play an important role in the pathogenesis of Alzheimer's disease (AD). However, the gene-gene interaction (epistasis) between specific allelic variants is only partially understood. OBJECTIVE: In our study, we examined the presence of the ɛ4 allele of apolipoprotein E (APOE) and the presence of C677T and A1298C (rs1801133 and rs1801131) polymorphisms in the...

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Identifiers

PMID: 32804129
DOI: 10.3233/JAD-200321
PMCID: PMC7683064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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