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Article

Methylenetetrahydrofolate reductase gene and risk of Alzheimer's disease in Koreans.

International journal of geriatric psychiatry - 1 May 2008

Kim Jae-Min, Stewart Robert, Kim Sung-Wan, Yang Su-Jin, Shin Il-Seon, Shin Hee-Young, Yoon Jin-Sang

Abstract excerpt

BACKGROUND: The association between methylenetetrahydrofolate reductase (MTHFR) c.677C>T (A222V) polymorphism and Alzheimer's disease (AD) is controversial. The objectives of the study were to investigate the association between MTHFR c.677C>T polymorphism and AD in Korean elders and to the extent to which it is modified by the major components of one-carbon metabolism and apolipoprotein E (APOE) genotype....

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Source

Identifiers

PMID: 17932993
DOI: 10.1002/gps.1903

Genes

MTHFR
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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