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Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy

17 Aug 2020

Abstract excerpt

Attention deficit hyperactive disorder (ADHD) is a highly heritable neurodevelopmental disorder, and excessive daytime sleepiness is frequently observed in ADHD patients. Excessive daytime sleepiness is also a core symptom of narcolepsy and essential hypersomnia (EHS), which are also heritable conditions. Psychostimulants are effective for the symptomatic control of ADHD (primary recommended intervention) and the...

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PMID: 32801330
DOI: 10.1038/s41398-020-00971-7

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