Article

Chandipura Virus forms cytoplasmic inclusion bodies through phase separation and proviral association of cellular protein Kinase R and stress granules protein TIA-1

2023-12-14

Abstract excerpt

Negative-strand RNA viruses form cytoplasmic inclusion bodies (IBs) representing virus replication foci through phase separation or bio-molecular condensation of viral and cellular proteins, as a hallmark of their infection. Alternatively, mammalian cells form stalled-mRNA containing antiviral stress granules (SGs), as a consequence of phosphorylation of eukaryotic initiation factor 2α (eIF2α) through condensation...

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Literature Corpus work: 14b1b0a2-4216-5449-8b31-dd3be9e5a538
DOI: 10.1101/2023.12.13.571494

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