Article
Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT.
Cancer biology & therapy - 1 Sept 2020
Handy Whitney F, Schmidt Keith T, Price Douglas K, Figg William D
Abstract excerpt
The Chemohormonal Therapy vs Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer (CHAARTED) was a randomized phase III trial that evaluated the outcomes of men with metastatic prostate cancer who received castration with or without docetaxel. Patients from this trial were genotyped in a recent study to detect HSD3B1 variance and to determine 2-y freedom from castration-resistant prostate...
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