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Article

Macrophage morphology correlates with single-cell diversity and prognosis in colorectal liver metastasis

26 Jun 2020

Abstract excerpt

It has long been known that in vitro polarized macrophages differ in morphology. Stemming from a conventional immunohistology observation, we set out to test the hypothesis that morphology of tumor-associated macrophages (TAMs) in colorectal liver metastasis (CLM) represents a correlate of functional diversity with prognostic significance. Density and morphological metrics of TAMs were measured and correlated...

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PMID: 32785653
DOI: 10.1084/jem.20191847

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