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Article

Derivation and Validation of Novel Phenotypes of Multiple Organ Dysfunction Syndrome in Critically Ill Children.

JAMA network open - 3 Aug 2020

Sanchez-Pinto L Nelson, Stroup Emily K, Pendergrast Tricia, Pinto Neethi, Luo Yuan

Abstract excerpt

Importance: Multiple organ dysfunction syndrome (MODS) is a dynamic and heterogeneous process associated with high morbidity and mortality in critically ill children. Objective: To determine whether data-driven phenotypes of MODS based on the trajectories of 6 organ dysfunctions have prognostic and therapeutic relevance in critically ill children. Design, Setting, and Participants: This cohort study included...

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Identifiers

PMID: 32780121
DOI: 10.1001/jamanetworkopen.2020.9271
PMCID: PMC7420303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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