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Histone methyltransferase Smyd3 is a new regulator for vascular senescence

11 Aug 2020

Abstract excerpt

Endothelial cell senescence is one of the main risk factors contributing to vascular diseases. As increasing number of "epigenetic drugs" entering clinical trials, understanding the mechanism of epigenetic regulation in vascular aging has significant implications in finding targets to cure vascular diseases. However, the epigenetic regulation of endothelial senescence remains unclear. Based on the findings that...

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PMID: 32779886
DOI: 10.1111/acel.13212

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