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How we approach Philadelphia chromosome‐positive acute lymphoblastic leukemia in children and young adults

11 Aug 2020

Abstract excerpt

Treatment for children with Philadelphia chromosome-positive acute lymphoblastic leukemia has changed radically over the past 20 years. This type of leukemia used to have dismal prognosis, but today cure rates have improved with combination of cytotoxic chemotherapy and a tyrosine kinase inhibitor such as imatinib or dasatinib, with hematopoietic stem cell transplant reserved for patients who are at high risk...

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PMID: 32779849
DOI: 10.1002/pbc.28543

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