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How I treat Philadelphia chromosome–positive acute lymphoblastic leukemia

16 Nov 2018

Abstract excerpt

The introduction of agents targeted at specific molecular events is changing the treatment paradigms in a number of malignancies. Historically, we have relied entirely on DNA-interactive, cytotoxic drugs for treating patients with leukemia. Increased understanding of the leukemic cell biology and pathogenesis, and the ways they evade the immune surveillance mechanisms, will likely lead to the development of more...

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PMID: 30442680
DOI: 10.1182/blood-2018-08-832105

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