Article
Mutational spectra of SARS-CoV-2 orf1ab polyprotein and signature mutations in the United States of America.
Journal of medical virology - 1 Mar 2021
Banerjee Shuvam, Seal Sohan, Dey Riju, Mondal Kousik Kr, Bhattacharjee Pritha
Abstract excerpt
The pandemic COVID-19 outbreak has been caused due to SARS-CoV-2 pathogen, resulting in millions of infections and deaths worldwide, the United States being on top at the present moment. The long, complex orf1ab polyproteins of SARS-CoV-2 play an important role in viral RNA synthesis. To assess the impact of mutations in this important domain, we analyzed 1134 complete protein sequences of the orf1ab polyprotein...
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