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Article

Prediction of the effects of the top 10 synonymous mutations from 26645 SARS-CoV-2 genomes of early pandemic phase.

F1000Research - 1 Jan 2021

Boon Wan Xin, Sia Boon Zhan, Ng Chong Han

Abstract excerpt

Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had led to a global pandemic since December 2019. SARS-CoV-2 is a single-stranded RNA virus, which mutates at a higher rate. Multiple works had been done to study nonsynonymous mutations, which change protein sequences. However, there is little study on the effects of SARS-CoV-2 synonymous mutations, which may affect viral...

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Source

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Identifiers

PMID: 39268187
DOI: 10.12688/f1000research.72896.3
PMCID: PMC11391198

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