Article

Mutational spectra of SARS-CoV-2 orf1ab polyprotein and Signature mutations in the United States of America

2020-05-01

Abstract excerpt

Pandemic COVID-19 outbreak has been caused due to SARS-COV2 pathogen, resulting millions of infection and death worldwide, USA being on top at the present moment. The long, complex orf1ab polyproteins of SARS-COV2 play an important role in viral RNA synthesis. To assess the impact of mutations in this important domain, we analyzed 1134 complete protein sequences of orf1ab polyprotein from NCBI Virus database from...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41aeb6a0-d0df-5562-8951-d4665b393550
DOI: 10.1101/2020.05.01.071654

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mutational spectra of SARS-CoV-2 orf1ab polyprotein and Signature mutations in the United States of AmericaDOI 10.1101/2020.05.01.071654Read

Mutational spectra of SARS-CoV-2 orf1ab polyprotein and signature mutations in the United States of America.Semantic proximity Read

Geographical Distribution of Amino Acid Mutations in Human SARS-CoV-2 Orf1ab Poly-Proteins Compared to the Equivalent Reference Proteins from ChinaSemantic proximity Read

Mutational Screening of the Proteome of Sars-Cov-2 Isolates: Mutability of ORF3a, Nucleocapsid and Nsp2 ProteinsSemantic proximity Read

Mutational Frequencies of SARS-CoV-2 Genome during the Beginning Months of the Outbreak in USASemantic proximity Read

Identification of Novel Missense Mutations in a Large Number of Recent SARS-CoV-2 Genome SequencesSemantic proximity Read

Mutational insights among the structural proteins of SARS-CoV-2: frequencies and evolutionary trends in American countriesSemantic proximity Read

Impact of clade specific mutations on structural fidelity of SARS-CoV-2 proteinsSemantic proximity Read

Genome composition and genetic characterization of SARS-CoV-2Semantic proximity Read

SARS-CoV-2 and ORF3a: Non-Synonymous Mutations and Polyproline RegionsSemantic proximity Read

Trends of mutation accumulation across global SARS-CoV-2 genomes: Implications for the evolution of the novel coronavirusSemantic proximity Read

Global landscape of SARS-CoV-2 mutations and conserved regions.Semantic proximity Read

SARS-COV-2: Analysis of mutational impacts on non-structural proteinsSemantic proximity Read