Article
CYP2 C9 polymorphism among patients with oral squamous cell carcinoma and its role in altering the metabolism of benzo[a]pyrene.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Sept 2020
R Hannah, Ramani Pratibha, Ramanathan Arvind, R Jancy Merlin, S Gheena, Ramasubramanian Abilasha, K Monika
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the prevalence of CYP2 C9 polymorphism among healthy controls and patients with oral squamous cell carcinoma (OSCC) and to analyze the risk of disease development. We also investigated the interaction between CYP2 C9 wild type and the polymorphic variants with benzo[a]pyrene by using molecular docking analysis. STUDY DESIGN: The study included 46 patients with...
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