Article
Splice variants of RAS-translational significance.
Cancer metastasis reviews - 1 Dec 2020
Rásó Erzsébet
Abstract excerpt
One of the mechanisms potentially explaining the discrepancy between the number of human genes and the functional complexity of organisms is generating alternative splice variants, an attribute of the vast majority of multi-exon genes. Members of the RAS family, such as NRAS, KRAS and HRAS, all of which are of significant importance in cancer biology, are no exception. The structural and functional differences of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
