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Article

Ras Isoforms from Lab Benches to Lives-What Are We Missing and How Far Are We?

International journal of molecular sciences - 17 Jun 2021

Nair Arathi, Kubatzky Katharina F, Saha Bhaskar

Abstract excerpt

The central protein in the oncogenic circuitry is the Ras GTPase that has been under intense scrutiny for the last four decades. From its discovery as a viral oncogene and its non-oncogenic contribution to crucial cellular functioning, an elaborate genetic, structural, and functional map of Ras is being created for its therapeutic targeting. Despite decades of research, there still exist lacunae in our...

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Identifiers

PMID: 34204435
DOI: 10.3390/ijms22126508
PMCID: PMC8233758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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