Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The (inner) world according to GARP: Genetic susceptibility and regulatory T cells.

Science immunology - 7 Aug 2020

Pillai Shiv

Abstract excerpt

A human autoimmune and allergic disease susceptibility variant on chromosome 11 results in the reduced expression of the gene encoding the GARP protein and thus compromises the function of regulatory T cells.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis
Share to Genetic Predisposition to Disease
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 32769174
DOI: 10.1126/sciimmunol.abe0976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The (inner) world according to GARP: Genetic susceptibility and regulatory T cells.PMID 32769174Read ↗

Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis.Semantic proximity Read ↗

Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk.Semantic proximity Read ↗

Population genetics and functions of the autoimmune regulator (AIRE).Semantic proximity Read ↗

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.Semantic proximity Read ↗

AIRE genetic variants and predisposition to polygenic autoimmune disease: The case of Graves' disease and a systematic literature review.Semantic proximity Read ↗

<i>VCAM1</i>-expressing T cells and systemic autoimmunity in Regnase-1 deficiencySemantic proximity Read ↗

AIRE-mutations and autoimmune disease.Semantic proximity Read ↗

A novel missense mutation in the AIRE gene underlying autoimmune polyglandular syndrome type 1.Semantic proximity Read ↗

Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE)Semantic proximity Read ↗

Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunitySemantic proximity Read ↗

An autoimmune disease risk SNP, rs2281808, in SIRPG is associated with reduced expression of SIRPγ and heightened effector state in human CD8 T-cellsSemantic proximity Read ↗

GIMAP GTPase family genes: potential modifiers in autoimmune diabetes, asthma, and allergy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.