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Article

Modified Jian-pi-yang-zheng decoction inhibits gastric cancer progression via the macrophage immune checkpoint PI3Kγ.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Sept 2020

Yuan Mengyun, Zou Xi, Liu Shenlin, Xu Xintian, Wang Hongxing, Zhu Min, Xie Xiaodong, Wang Haidan, Wu Jian, Sun Qingmin

Abstract excerpt

Jian-pi-yang-zheng Decoction (JPYZ) is a traditional Chinese medicine that is used for the treatment of advanced gastric cancer, and it shows good efficacy in patients. A previous study indicated that JPYZ inhibited the progression of gastric cancer via the regulation of tumor-associated macrophages (TAMs), but the underlying molecular target of JPYZ regulation of TAMs has not been determined. The present study...

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Identifiers

PMID: 32768942
DOI: 10.1016/j.biopha.2020.110440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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