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Huazhuojiedu Decoction Regulates Mitophagy to Alleviate Precancerous Lesions of Gastric Cancer via Sirt3/Foxo3a/Parkin Pathway

2023-04-04

Abstract excerpt

Backgroud： Huazhuojiedu decoction (HZJD) has been demonstrated to be effective in the treatment of precancerous lesions of gastric cancer (PLGC). We aimed to explore the potential mechanisms of HZJD for alleviating PLGC in vivo and in vitro. <h4>Methods: </h4>: The PLGC rat model was established by administrating 1-Methyl-3-nitro-1-nitrosoguanidine (MNNG) and sodium for 24 weeks, followed by 10 weeks of HZJD deco...

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Literature Corpus work: bf3763b1-8be7-59eb-b18d-2543778aa4e3
DOI: 10.21203/rs.3.rs-2592727/v1

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