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Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomas

6 Aug 2020

Abstract excerpt

Abstract Background Immunotherapies targeting glioblastoma (GBM) have led to significant improvements in patient outcomes. TOX is closely associated with the immune environment surrounding tumors, but its role in gliomas is not fully understood. Methods Using data from The Cancer Genome Atlas (TCGA) and the Chinese Glioma Genome Atlas (CGGA), we analyzed the transcriptomes of 1691 WHO grade I-IV human glioma...

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PMID: 32762688
DOI: 10.1186/s12967-020-02460-3

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