Article
Reverse expression pattern of sirtuin-1 and histone deacetylase-9 in coronary artery disease.
Archives of physiology and biochemistry - 1 Feb 2023
Heidari Laleh, Ghaderian Sayyed Mohammad Hossein, Bastami Milad, Hosseini Shadi, Alipour Parsa Saeed, Heidari Sahel, Jafari Hossein, Sohrabifar Nasim, Pirhoushiaran Maryam
Abstract excerpt
BACKGROUND: SIRT1 and HDAC 9 genes are related to inflammation and may contribute to the pathogenesis of coronary artery disease (CAD). We aimed to evaluate the expression level, methylation profile and polymorphisms of these genes in CAD patients. METHODS: In this study, 50 CAD patients and 50 healthy individuals were recruited. The expression level change was evaluated using the TaqMan Real-Time PCR method. The...
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