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Article

HDAC9 Variant Rs2107595 Modifies Susceptibility to Coronary Artery Disease and the Severity of Coronary Atherosclerosis in a Chinese Han Population.

PloS one - 1 Jan 2016

Wang Xue-Bin, Han Ya-di, Sabina Shrestha, Cui Ning-Hua, Zhang Shuai, Liu Ze-Jin, Li Cong, Zheng Fang

Abstract excerpt

A previous genome-wide association study showed that a single nucleotide polymorphism (SNP) rs2107595 in histone deacetylase 9 (HDAC9) gene was associated with large artery stroke (LAS) in Caucasians. Based on the similar atherosclerotic pathogenesis between LAS and coronary artery disease (CAD), we aimed to evaluate the associations of SNP rs2107595 with CAD risk and the severity of coronary atherosclerosis in a...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27494404
DOI: 10.1371/journal.pone.0160449
PMCID: PMC4975504

Genes

CAD
HDAC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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