Article
Bacterial Evolution in High-Osmolarity Environments.
mBio - 4 Aug 2020
Cesar Spencer, Anjur-Dietrich Maya, Yu Brian, Li Ethan, Rojas Enrique, Neff Norma, Cooper Tim F, Huang Kerwyn Casey
Abstract excerpt
Bacteria must maintain a cytosolic osmolarity higher than that of their environment in order to take up water. High-osmolarity environments therefore present formidable stress to bacteria. To explore the evolutionary mechanisms by which bacteria adapt to high-osmolarity environments, we selected Escherichia coli in media with a variety of osmolytes and concentrations for 250 generations. Adaptation was osmolyte...
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