Article

Osmotic conditions shape fitness gains and resistance mechanisms during <i>E. coli</i> and T4 phage co-evolution

2025-03-15

Abstract excerpt

Environmental conditions strongly influence interactions between bacteria and bacterio-phages (phages). Here, we examined how osmolality (solute concentration) shapes the in vitro co-evolution of T4 phage and its host Escherichia coli during serial passage. When evolved independently, we observed substantial fitness gains in both bacteria and phages, particularly in high osmotic conditions. During co-evolution, h...

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Literature Corpus work: 25f67b31-4cd2-5aac-8bb0-9f3e97f2841e
DOI: 10.1101/2025.03.14.643354

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