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Article

Coordinated regulation of anthranilate metabolism and bacterial virulence by the GntR family regulator MpaR in Pseudomonas aeruginosa.

Molecular microbiology - 1 Nov 2020

Wang Tietao, Qi Yihang, Wang Zhihan, Zhao Jingru, Ji Linxuan, Li Jun, Cai Zhao, Yang Liang, Wu Min, Liang Haihua

Abstract excerpt

The GntR family regulators are widely distributed in bacteria and play critical roles in metabolic processes and bacterial pathogenicity. In this study, we describe a GntR family protein encoded by PA4132 that we named MpaR (MvfR-mediated PQS and anthranilate regulator) for its regulation of Pseudomonas quinolone signal (PQS) production and anthranilate metabolism in Pseudomonas aeruginosa. The deletion of mpaR...

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PMID: 32748556
DOI: 10.1111/mmi.14584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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