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Article

The Atypical Response Regulator AtvR Is a New Player in Pseudomonas aeruginosa Response to Hypoxia and Virulence.

Infection and immunity - 1 Aug 2017

Kaihami Gilberto Hideo, Breda Leandro Carvalho Dantas, de Almeida José Roberto Fogaça, de Oliveira Pereira Thays, Nicastro Gianlucca Gonçalves, Boechat Ana Laura, de Almeida Sandro Rogério, Baldini Regina Lúcia

Abstract excerpt

Two-component systems are widespread in bacteria, allowing adaptation to environmental changes. The classical pathway is composed of a histidine kinase that phosphorylates an aspartate residue in the cognate response regulator (RR). RRs lacking the phosphorylatable aspartate also occur, but their function and contribution during host-pathogen interactions are poorly characterized. AtvR (PA14_26570) is the only...

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Identifiers

PMID: 28533471
DOI: 10.1128/IAI.00207-17
PMCID: PMC5520423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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